Name
ahi_primary
Label
Apnea-Hypopnea Index: (All apneas with no oxygen desaturation threshold used + hypopneas with > 30% flow reduction and with >= 4% oxygen desaturation) / hour of estimated sleep from type III home sleep apnea test
Description

Calculated - Summary metric of sleep disordered breathing events. The definition of hypopnea events is consistent with the following clinical guidelines: (1) AASM 2012 update (alternative) Berry RB et al. 2012 (PubMed ID:23066376), and (2) AASM 2015 (acceptable) [Berry RB et al. The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications, Version 2.2. American Academy of Sleep Medicine, Darien, IL, 2015.].

Units
events per hour
Type
numeric
Visit number vs Apnea-Hypopnea Index: (All apneas with no oxygen desaturation threshold used + hypopneas with > 30% flow reduction and with >= 4% oxygen desaturation) / hour of estimated sleep from type III home sleep apnea test
N Mean StdDev Median Min Max Unknown Total
Baseline Visit 169 29.2 ± 16.6 23.9 6.7 108.4 - 169
Month-6 Follow-up Visit 47 13.9 ± 12.6 12.3 0.4 50.7 122 169
Month-12 Follow-up Visit 44 16.5 ± 13.9 12.7 0.2 68.0 64 108
Treatment arm vs Apnea-Hypopnea Index: (All apneas with no oxygen desaturation threshold used + hypopneas with > 30% flow reduction and with >= 4% oxygen desaturation) / hour of estimated sleep from type III home sleep apnea test
Baseline Visit
N Mean StdDev Median Min Max Unknown Total
Total 169 29.2 ± 16.6 23.9 6.7 108.4 - 169
Conservative Medical Therapy (CMT) 44 32.6 ± 20.1 26.1 15.1 108.4 - 44
CMT + Sham CPAP 42 31.4 ± 18.1 25.6 15.0 87.9 - 42
CMT + Active CPAP 42 25.7 ± 12.5 23.7 6.7 68.3 - 42
CMT + Active CPAP + Motivational Enhancement 41 26.7 ± 13.5 21.8 10.7 60.6 - 41
Treatment arm vs Apnea-Hypopnea Index: (All apneas with no oxygen desaturation threshold used + hypopneas with > 30% flow reduction and with >= 4% oxygen desaturation) / hour of estimated sleep from type III home sleep apnea test
Month-6 Follow-up Visit
N Mean StdDev Median Min Max Unknown Total
Total 47 13.9 ± 12.6 12.3 0.4 50.7 122 169
Conservative Medical Therapy (CMT) 11 19.1 ± 11.1 17.6 3.3 45.1 33 44
CMT + Sham CPAP 10 19.5 ± 14.4 15.3 3.5 50.7 32 42
CMT + Active CPAP 14 13.1 ± 13.0 9.3 0.4 43.4 28 42
CMT + Active CPAP + Motivational Enhancement 12 5.3 ± 6.4 3.2 0.5 23.6 29 41
Treatment arm vs Apnea-Hypopnea Index: (All apneas with no oxygen desaturation threshold used + hypopneas with > 30% flow reduction and with >= 4% oxygen desaturation) / hour of estimated sleep from type III home sleep apnea test
Month-12 Follow-up Visit
N Mean StdDev Median Min Max Unknown Total
Total 44 16.5 ± 13.9 12.7 0.2 68.0 64 108
Conservative Medical Therapy (CMT) 15 22.6 ± 15.7 21.2 5.0 68.0 14 29
CMT + Sham CPAP 12 17.1 ± 13.9 14.0 0.2 39.8 15 27
CMT + Active CPAP 5 12.3 ± 10.1 12.6 0.5 24.3 21 26
CMT + Active CPAP + Motivational Enhancement 12 9.9 ± 10.4 6.2 0.4 26.6 14 26
Age at visit vs Apnea-Hypopnea Index: (All apneas with no oxygen desaturation threshold used + hypopneas with > 30% flow reduction and with >= 4% oxygen desaturation) / hour of estimated sleep from type III home sleep apnea test
Baseline Visit
N Mean StdDev Median Min Max Unknown Total
Total 169 29.2 ± 16.6 23.9 6.7 108.4 - 169
46.0 to 59.0 years 43 28.0 ± 13.6 24.7 6.7 65.1 - 43
59.0 to 66.0 years 42 31.7 ± 21.3 22.0 9.6 108.4 - 42
66.0 to 69.0 years 42 28.5 ± 15.2 23.6 6.8 72.5 - 42
70.0 to 76.0 years 42 28.4 ± 15.5 24.7 15.0 87.9 - 42
Age at visit vs Apnea-Hypopnea Index: (All apneas with no oxygen desaturation threshold used + hypopneas with > 30% flow reduction and with >= 4% oxygen desaturation) / hour of estimated sleep from type III home sleep apnea test
Month-6 Follow-up Visit
N Mean StdDev Median Min Max Unknown Total
Total 47 13.9 ± 12.6 12.3 0.4 50.7 122 169
46.0 to 60.0 years 7 6.1 ± 6.8 3.6 0.5 19.6 36 43
60.0 to 66.0 years 10 13.0 ± 11.2 12.0 1.4 37.5 32 42
66.0 to 70.0 years 17 17.1 ± 15.0 15.2 0.4 50.7 25 42
70.0 to 77.0 years 13 14.5 ± 11.7 13.4 2.1 43.4 29 42
Age at visit vs Apnea-Hypopnea Index: (All apneas with no oxygen desaturation threshold used + hypopneas with > 30% flow reduction and with >= 4% oxygen desaturation) / hour of estimated sleep from type III home sleep apnea test
Month-12 Follow-up Visit
N Mean StdDev Median Min Max Unknown Total
Total 44 16.5 ± 13.9 12.7 0.2 68.0 64 108
47.0 to 60.0 years 10 17.7 ± 15.0 14.9 0.7 39.8 17 27
60.0 to 66.0 years 14 18.5 ± 18.3 15.0 0.2 68.0 13 27
66.0 to 70.0 years 12 13.4 ± 9.5 11.7 0.5 26.6 15 27
71.0 to 77.0 years 8 15.9 ± 10.6 13.7 5.5 37.5 19 27
Gender vs Apnea-Hypopnea Index: (All apneas with no oxygen desaturation threshold used + hypopneas with > 30% flow reduction and with >= 4% oxygen desaturation) / hour of estimated sleep from type III home sleep apnea test
Baseline Visit
N Mean StdDev Median Min Max Unknown Total
Total 169 29.2 ± 16.6 23.9 6.7 108.4 - 169
Male 110 29.4 ± 15.4 25.0 6.8 87.9 - 110
Female 59 28.6 ± 18.6 21.3 6.7 108.4 - 59
Gender vs Apnea-Hypopnea Index: (All apneas with no oxygen desaturation threshold used + hypopneas with > 30% flow reduction and with >= 4% oxygen desaturation) / hour of estimated sleep from type III home sleep apnea test
Month-6 Follow-up Visit
N Mean StdDev Median Min Max Unknown Total
Total 47 13.9 ± 12.6 12.3 0.4 50.7 122 169
Male 32 15.0 ± 13.7 12.9 0.4 50.7 78 110
Female 15 11.4 ± 9.6 9.4 0.5 37.5 44 59
Gender vs Apnea-Hypopnea Index: (All apneas with no oxygen desaturation threshold used + hypopneas with > 30% flow reduction and with >= 4% oxygen desaturation) / hour of estimated sleep from type III home sleep apnea test
Month-12 Follow-up Visit
N Mean StdDev Median Min Max Unknown Total
Total 44 16.5 ± 13.9 12.7 0.2 68.0 64 108
Male 31 17.4 ± 14.7 16.8 0.2 68.0 41 72
Female 13 14.3 ± 12.2 9.7 0.5 34.0 23 36
Race vs Apnea-Hypopnea Index: (All apneas with no oxygen desaturation threshold used + hypopneas with > 30% flow reduction and with >= 4% oxygen desaturation) / hour of estimated sleep from type III home sleep apnea test
Baseline Visit
N Mean StdDev Median Min Max Unknown Total
Total 168 29.3 ± 16.5 24.0 6.7 108.4 - 168
White 152 29.2 ± 16.7 24.0 6.7 108.4 - 152
American Indian or Alaskan Native - - - - - - - -
Black or African American 11 29.8 ± 11.6 29.5 17.2 49.8 - 11
Asian 4 18.5 ± 5.4 16.4 14.9 26.5 - 4
Native Hawaiian or other Pacific islander - - - - - - - -
Other 1 72.4 - 72.4 72.4 72.4 - 1
Multiple - - - - - - - -
Race vs Apnea-Hypopnea Index: (All apneas with no oxygen desaturation threshold used + hypopneas with > 30% flow reduction and with >= 4% oxygen desaturation) / hour of estimated sleep from type III home sleep apnea test
Month-6 Follow-up Visit
N Mean StdDev Median Min Max Unknown Total
Total 46 14.1 ± 12.6 12.9 0.4 50.7 122 168
White 44 14.3 ± 12.8 12.9 0.4 50.7 108 152
American Indian or Alaskan Native - - - - - - - -
Black or African American 1 2.2 - 2.2 2.2 2.2 10 11
Asian 1 15.7 - 15.7 15.7 15.7 3 4
Native Hawaiian or other Pacific islander - - - - - - - -
Other - - - - - - 1 1
Multiple - - - - - - - -
Race vs Apnea-Hypopnea Index: (All apneas with no oxygen desaturation threshold used + hypopneas with > 30% flow reduction and with >= 4% oxygen desaturation) / hour of estimated sleep from type III home sleep apnea test
Month-12 Follow-up Visit
N Mean StdDev Median Min Max Unknown Total
Total 44 16.5 ± 13.9 12.7 0.2 68.0 64 108
White 41 15.9 ± 13.9 12.6 0.2 68.0 54 95
American Indian or Alaskan Native - - - - - - - -
Black or African American 2 22.8 ± 18.5 22.8 9.7 35.9 7 9
Asian 1 28.8 - 28.8 28.8 28.8 2 3
Native Hawaiian or other Pacific islander - - - - - - - -
Other - - - - - - 1 1
Multiple - - - - - - - -