We use cookies and other tools to enhance your experience on our website and to analyze our web traffic.
For more information about these cookies and the data collected, please refer to our Privacy Policy.

Cleveland Family Study

Name Label Folder
nsrr_bmi
Body mass index (BMI)
Body mass index (BMI)

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: bmi at Visit 5

Harmonized/Anthropometry
nsrr_bp_diastolic
Diastolic blood pressure
Diastolic blood pressure

Average resting diastolic blood pressure of two measurements collected from the upper arm in a single clinic visit. When more than two measurements were collected, the average was calculated using the second and third measurements. In cases where either of the measurements was missing, the average was calculated discarding the missing value.

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: dbp at Visit 5

Harmonized/Clinical Data
nsrr_bp_systolic
Systolic blood pressure
Systolic blood pressure

Average resting systolic blood pressure of two measurements collected from the upper arm in a single clinic visit. When more than two measurements were collected, the average was calculated using the second and third measurements. In cases where either of the measurements was missing, the average was calculated discarding the missing value.

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: sbp at Visit 5

Harmonized/Clinical Data
nsrr_age
Subject age
Subject age

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: age at Visit 5

Harmonized/Demographics
nsrr_age_gt89
Indicates whether the subject's age (in years) used during date obfuscation is greater than 89 years
Indicates whether the subject's age (in years) used during date obfuscation is greater than 89 years

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: age at Visit 5

Harmonized/Demographics
nsrr_ethnicity
Subject ethnicity
Subject ethnicity

Original missing value is recoded as "not reported".

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: ethnicity at Visit 5

Harmonized/Demographics
nsrr_race
Subject race
Subject race

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: race at Visit 5

Harmonized/Demographics
nsrr_sex
Subject sex
Subject sex

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: male at Visit 5

Harmonized/Demographics
nsrr_current_smoker
Currently smoking cigarettes
Currently smoking cigarettes

Indicates whether subject currently smokes cigarettes.

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: nowsmoke, monsmoke at Visit 5

Harmonized/Lifestyle and Behavioral Health
nsrr_ever_smoker
Ever smoked cigarettes
Ever smoked cigarettes

Indicates whether subject ever regularly smoked cigarettes.

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: smoked at Visit 5

Harmonized/Lifestyle and Behavioral Health
nsrr_ahi_hp3r_aasm15
Apnea-Hypopnea Index : (All apneas + hypopneas with >=30% nasal cannula [or alternative sensor] reduction and >= 3% oxygen desaturation or with arousal) / hour of sleep
Apnea-Hypopnea Index : (All apneas + hypopneas with >=30% nasal cannula [or alternative sensor] reduction and >= 3% oxygen desaturation or with arousal) / hour of sleep

Harmonized by the NSRR team.

The definition for hypopneas is consistent with the following clinical guidelines: (1) American Academy of Sleep Medicine (AASM) 2007 Manual (2012 update) (recommended). Berry RB et al. 2012 (PubMed ID:23066376), and (2) American Academy of Sleep Medicine (AASM) 2015 (recommended) [Berry RB et al. The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications, Version 2.2. American Academy of Sleep Medicine, Darien, IL, 2015.]

Refer to the source for detailed definition for respiratory events: ahi_a0h3a at Visit 5

Harmonized/Polysomnography/Apnea-Hypopnea Indices
nsrr_ahi_hp3u
Apnea-Hypopnea Index : (All apneas + hypopneas with >= 3% oxygen desaturation) / hour of sleep
Apnea-Hypopnea Index : (All apneas + hypopneas with >= 3% oxygen desaturation) / hour of sleep

Harmonized by the NSRR team. Refer to the source for detailed definition for respiratory events: ahi_a0h3 at Visit 5

Harmonized/Polysomnography/Apnea-Hypopnea Indices
nsrr_ahi_hp4r
Apnea-Hypopnea Index : (All apneas + hypopneas with >= 4% oxygen desaturation or with arousal) / hour of sleep
Apnea-Hypopnea Index : (All apneas + hypopneas with >= 4% oxygen desaturation or with arousal) / hour of sleep

Harmonized by the NSRR team. Refer to the source for detailed definition for respiratory events: ahi_a0h4a at Visit 5

Harmonized/Polysomnography/Apnea-Hypopnea Indices
nsrr_ahi_hp4u_aasm15
Apnea-Hypopnea Index : (All apneas + hypopneas with >=30% nasal cannula [or alternative sensor] reduction with >= 4% oxygen desaturation) / hour of sleep
Apnea-Hypopnea Index : (All apneas + hypopneas with >=30% nasal cannula [or alternative sensor] reduction with >= 4% oxygen desaturation) / hour of sleep

Harmonized by the NSRR team.

The definition of hypopnea events is consistent with the following clinical guidelines: (1) AASM 2012 update (alternative) Berry RB et al. 2012 (PubMed ID:23066376), and (2) AASM 2015 (acceptable) [Berry RB et al. The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications, Version 2.2. American Academy of Sleep Medicine, Darien, IL, 2015.].

Refer to the source for detailed definition for respiratory events: ahi_a0h4 at Visit 5

Harmonized/Polysomnography/Apnea-Hypopnea Indices
nsrr_phrnumar_f1
Arousal Index: Number of arousals per hour of sleep from polysomnography
Arousal Index: Number of arousals per hour of sleep from polysomnography

Harmonized by the NSRR team. Source: ai_all at Visit 5

Harmonized/Polysomnography/Arousal
nsrr_flag_spsw
Study scored sleep/wake rather than with full sleep staging if there is not sufficient quality on EEG lead. Studies scored as sleep wake have all sleep stages scored using a default of Stage 2 and no arousals are scored.
Study scored sleep/wake rather than with full sleep staging if there is not sufficient quality on EEG lead. Studies scored as sleep wake have all sleep stages scored using a default of Stage 2 and no arousals are scored.

Harmonized by the NSRR team. Source: slewake at Visit 5

Harmonized/Polysomnography/Signal Quality
nsrr_ttldursp_f1
Total Sleep Duration: the interval between sleep onset and sleep offset while the participant is asleep from polysomnography
Total Sleep Duration: the interval between sleep onset and sleep offset while the participant is asleep from polysomnography

Conventionally, this would be called total sleep time (TST) (i.e. total time spent in stage 1 or greater).

Harmonized by the NSRR team. Source: slpprdp at Visit 5

Harmonized/Polysomnography/Sleep Architecture