Mignot Nature Communications
EDF Harmonization Process
Signal harmonization
- Using Luna, a list of all channel names were extracted from the EDFs for the Mignot Nature Communication cohorts. Subsequently, the channel names in EDF files were changed to a new set of standardized channel names listed on the montage page under "EDF Label".
- The DHC cohort provided recordings in .mat format, these were converted to EDF
- A few EDFs contained additional EEG channels Fz_M1, Fz_M2, and M1_M2, these were removed.
- Polarity checks were performed via Luna. EEG traces in the DHC cohort were flipped to correct polarity, with upwards deflections indicating negative polarity.
- Several EEG channels were recorded in mV, they were changed to uV.
- Finally, canonical channels cs_EEG, cs_EMG, and cs_EEG were generated at a sample rate of 100Hz and added to each EDF. The table below lists the channels used as input by Luna.
| TYPE | CHANNEL | REF | SAMPLING RATE | NOTES |
|---|---|---|---|---|
| EEG | C4 | M1 | 100 | |
| EEG | C4 | . | 100 | |
| EMG | rchin | lchin | 100 | |
| EMG | chin | . | 100 | Using linked EMG |
| EMG | cchin_l | . | 100 | Using linked EMG |
| ECG | ECG1 | ECG2,ECG3 | 100 | |
| ECG | ECG,ECG2 | . | 100 | |
| ECG | ECG1_2 | . | 100 | Using linked ECG |
Annotation harmonization
- 3 cohorts provided scoring annotations: SSC, CNC, and DHC.
- SSC and CNC annotations were converted from .sta format to Luna's .eannot format
- DHC annotations were converted from .mat format to Luna's .eannot format
- .eannot files were then harmonized. Stage N4 was changed to N3. All .eannot files now have the following staging encoding: wake, N1, N2, N3, REM, unscored