The Best Apnea Interventions for Research (BestAIR) study aimed to randomize approximately 180 patients with sleep apnea who had either established CVD or at least three CVD risk factors into a 12-mo, four-arm intervention study. All arms included nightly use of nasal dilator strips and conservative medical therapy (CMT) defined as education on healthy sleep and lifestyle. The two active arms were: (1) active CPAP delivered using standard support from a trained sleep technician; and (2) active CPAP enhanced by a behavioral promotion intervention delivered by a behavioral therapist. The two control arms were: (1) sham-CPAP; and (2) CMT alone. The primary physiological outcome was change in mean 24-h systolic blood pressure. Process measures were recruitment yields, retention rates, and CPAP adherence levels.
The Apnea, Bariatric surgery, and CPAP (ABC) study is a randomized trial of CPAP versus laparoscopic gastric banding (LGB) for patients with severe obstructive sleep apnea (OSA), hypothesizing that residual disease (effective apnea-hypopnea index [AHI]) and Epworth Sleepiness Scale (ESS) would be significantly lower with LGB compared to CPAP at 9- and 18-months.
The subject wore an actigraph on his wrist for 365 consecutive days. The main purpose of the project is to search for predictive algorithms from wrist actigraphy recordings of one subject using a MotionWatch8 (CamNtech Ltd) system on the non predominant wrist, for unrestricted lifestyle.