Related Variables

age Age at time of visit Demographics
nsrr_bmi Body mass index (BMI)

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: :bmi: at Visit 3

Harmonized/Anthropometry
nsrr_bp_diastolic Diastolic blood pressure

Average resting diastolic blood pressure of six measurements (three measurements in the evening and three in the morning) collected from the upper arm in a single day. In cases where either of the measurements was missing, the average was calculated discarding the missing value.

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: :bpdias: at Visit 3

Harmonized/Clinical Data
nsrr_bp_systolic Systolic blood pressure

Average resting systolic blood pressure of six measurements (three measurements in the evening and three in the morning) collected from the upper arm in a single day. In cases where either of the measurements was missing, the average was calculated discarding the missing value.

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: :bpsys: at Visit 3

Harmonized/Clinical Data
nsrr_age Subject age

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: :age: at Visit 3

Harmonized/Demographics
nsrr_age_gt89 Indicates whether the subject's age (in years) used during date obfuscation is greater than 89 years

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: :age: at Visit 3

Harmonized/Demographics
nsrr_ethnicity Subject ethnicity

Original missing value is recoded as "not reported".

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: :ethnicity: at Visit 3

Harmonized/Demographics
nsrr_race Subject race

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: :race: at Visit 3

Harmonized/Demographics
nsrr_sex Subject sex

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: :male: at Visit 3

Harmonized/Demographics
nsrr_current_smoker Currently smoking cigarettes

Indicates whether subject currently smokes cigarettes.

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: :yevrsmk: , :ycursmk: at Visit 3

Harmonized/Lifestyle and Behavioral Health
nsrr_ever_smoker Ever smoked cigarettes

Indicates whether subject ever regularly smoked cigarettes.

Harmonized by the NSRR team to align with TOPMed and BioDataCatalyst standards. Source: :yevrsmk: at Visit 3

Harmonized/Lifestyle and Behavioral Health
nsrr_ahi_hp3r_aasm15 Apnea-Hypopnea Index : (All apneas + hypopneas with >=30% nasal cannula [or alternative sensor] reduction and >= 3% oxygen desaturation or with arousal) / hour of sleep

Harmonized by the NSRR team.

The definition for hypopneas is consistent with the following clinical guidelines: (1) American Academy of Sleep Medicine (AASM) 2007 Manual (2012 update) (recommended). Berry RB et al. 2012 (PubMed ID:23066376), and (2) American Academy of Sleep Medicine (AASM) 2015 (recommended) [Berry RB et al. The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications, Version 2.2. American Academy of Sleep Medicine, Darien, IL, 2015.]

Refer to the source for detailed definition for respiratory events: :ahi_a0h3a: at Visit 3

Harmonized/Polysomnography/Apnea-Hypopnea Indices
nsrr_ahi_hp3u Apnea-Hypopnea Index : (All apneas + hypopneas with >= 3% oxygen desaturation) / hour of sleep

Harmonized by the NSRR team. Refer to the source for detailed definition for respiratory events: :ahi_a0h3: at Visit 3

Harmonized/Polysomnography/Apnea-Hypopnea Indices
nsrr_ahi_hp4r Apnea-Hypopnea Index : (All apneas + hypopneas with >= 4% oxygen desaturation or with arousal) / hour of sleep

Harmonized by the NSRR team. Refer to the source for detailed definition for respiratory events: :ahi_a0h4a: at Visit 3

Harmonized/Polysomnography/Apnea-Hypopnea Indices
nsrr_ahi_hp4u_aasm15 Apnea-Hypopnea Index : (All apneas + hypopneas with >=30% nasal cannula [or alternative sensor] reduction with >= 4% oxygen desaturation) / hour of sleep

Harmonized by the NSRR team.

The definition of hypopnea events is consistent with the following clinical guidelines: (1) AASM 2012 update (alternative) Berry RB et al. 2012 (PubMed ID:23066376), and (2) AASM 2015 (acceptable) [Berry RB et al. The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications, Version 2.2. American Academy of Sleep Medicine, Darien, IL, 2015.].

Refer to the source for detailed definition for respiratory events: :ahi_a0h4: at Visit 3

Harmonized/Polysomnography/Apnea-Hypopnea Indices
nsrr_phrnumar_f1 Arousal Index: Number of arousals per hour of sleep from polysomnography

Harmonized by the NSRR team. Source: :ai_all: at Visit 3

Harmonized/Polysomnography/Arousal
nsrr_flag_spsw Study scored sleep/wake rather than with full sleep staging if there is not sufficient quality on EEG lead. Studies scored as sleep wake have all sleep stages scored using a default of Stage 2 and no arousals are scored.

Harmonized by the NSRR team. Source: :slewake: at Visit 3

Harmonized/Polysomnography/Signal Quality
nsrr_tst_f1 Total Sleep Duration: the interval between sleep onset and sleep offset while the participant is asleep from polysomnography

Conventionally, this would be called total sleep time (TST) (i.e. total time spent in stage 1 or greater).

Harmonized by the NSRR team. Source: :slpprdp: at Visit 3

Harmonized/Polysomnography/Sleep Architecture